Premarin are mostly used as hormone replacement for menopausal women. It helps to treat hot flashes and prevent osteoporosis. It is also used to treat women with low hormone levels or those who have had their ovaries removed.
Active Ingredient: conjugated estrogens usp
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Premarin (Conjugated Estrogens Usp)
Conjugated Estrogens tablet
What is it used for?
CONJUGATED ESTROGENS are mostly used as hormone replacement for menopausal women. It helps to treat hot flashes and prevent osteoporosis. It is also used to treat women with low hormone levels or those who have had their ovaries removed.
What should I discuss with my physician prior to taking this medicine?
Please do tell your physician if you have any of the following conditions:
- abnormal vaginal bleeding
- blood vessel disease or blood clots
- breast, cervical, endometrial, ovarian, liver, or uterine cancer
- gallbladder disease
- heart disease or recent heart attack
- high blood pressure
- high cholesterol
- high level of calcium in the blood
- kidney disease
- liver disease
- mental depression
- migraine headaches
- tobacco smoker
- an unusual or allergic reaction to estrogens, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How is this medicine should be taken?
Take it orally accompanied with a glass of water. Take your medicine at the regular intervals, at the same time each day. You should never take this medicine more often than prescribed.
Consult with your pediatrician regarding the possibility of use of this medicine by children. This medicine is not approved for use by children.
Overdosage: If you suspect an overdosage, get in touch with the nearest poison control center or emergency room immediately.
NOTE: This medicine is only intended for your use. You should never share it with the others.
What to do if I missed a dose?
If you missed a dose, it should be taken as soon as possible. If the time has almost come for the next dose, only that one should be taken. You should never take double or extra doses; a single doze is sufficient for the purposes.
What are the possible interactions with the other medicine/food/etc?
This medicine should never be taken with any of the following drugs:
- aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
It may also trigger possible interactions with the following:
- barbiturates, such as phenobarbital
- grapefruit juice
- medicines for fungal infections like ketoconazole and itraconazole
- St. John's Wort
- thyroid hormones
This list is not all-inclusive. Provide your health care provider with a list of all the medicines, herbs, non-prescription drugs, or dietary supplements that you use. Also tell them whether you smoke, drink alcohol, or use illegal drugs. Some of those items may also interact with your medicine.
Is there anything I should pay attention to while taking it?
Visit your health care professional for the regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine. You should also discuss the need for the regular mammograms with your health care professional, and follow their guidelines for these tests.
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
If you have any reason to think you are pregnant; stop taking this medicine right away and contact your doctor or health care professional.
Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are older than 35 years old. You are strongly advised not to smoke.
If you wear contact lenses and notice any visual changes, or if the lenses begin to feel uncomfortable, consult with your eye care specialist.
This medicine can increase the risk of developing a condition (endometrial hyperplasia) that may lead to a cancer of the lining of the uterus. Taking progestins, another hormone drug, with this medicine lowers the risk of developing this condition. Therefore, if your uterus has not been removed (by a hysterectomy), your doctor may prescribe a progestin for you to take it together with your estrogen. You should know, however, that taking estrogens with progestins may have additional health risks. You should discuss the use of estrogens and progestins with your health care professional to determine the benefits and risks for you.
If you are going to have a surgery, you may need to stop taking this medicine. Consult with your health care professional for advice before you schedule the surgery.
Does this medicine have any possible side effects?
The following side effects should be reported to your doctor or health care professional as soon as they are noticed:
- allergic reactions like skin rashes, itching or hives,face, lips, or tongue swelling
- breast tissue changes or discharge
- changes in vision
- chest pains
- confusion, trouble speaking or understanding
- dark urine
- general ill feeling or flu-like symptoms
- light-colored stools
- nausea, vomiting
- pain, swelling, warmth in the leg
- right upper belly pain
- severe headaches
- shortness of breath
- sudden numbness or weakness of the face, arm or leg
- trouble walking, dizziness, loss of balance or coordination
- unusual vaginal bleeding
- yellowing of the eyes or skin
The side effects listed below usually do not necessarily require any medical attention (please do report them to your physician if they are recurrent or bothersome):
- hair loss
- increased hunger or thirst
- increased urination
- symptoms of vaginal infection like itching, irritation or unusual discharge
- unusual weakness or feeling tired
Other side effects are also possible, the above list is not all inclusive.
Where should I keep my medicine?
Keep this medicine out of the children’s reach.
This medicine should be stored at the room temperatures between 15 and 30 degrees C (59 and 86 degrees F). Dispose of any unused medicine after the expiry date is reached.
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